Pharmaceutical Accumulation in the Environment: Prevention, Control, Health Effects, and Economic Impact
Editor: Walter E. Goldstein, Goldstein Consulting Company
Sick Building Syndrome and Related Illness: Prevention and Remediation of Mold Contamination.
Editor: Walter E. Goldstein, Goldstein Consulting Company
120 Emerald Forest St., Unit #103
Las Vegas, Nevada 89145-3987
Dr. Walter E. Goldstein is the President of Goldstein Consulting Company. He is also President and co-founder of a biomedical business with the objective to produce Universal Blood. He was the Coordinator of the Biotechnology Center, Shadow Lane Campus, University of Nevada Las Vegas from 2003-2008. He is an executive with 40-plus years of experience developing technology, products, and business. He led a research and development organization of 140 persons (35 Ph.D.'s) at Bayer (Miles, Inc.), a leading firm in biotechnology, clinical diagnostics, therapeutics, food ingredients, materials, chemicals, and consumer products. He led 35 persons (10 Ph.D.'s) at ESCAgenetics Corporation, which was a leading developer of plant-based technology for food, food ingredients and pharmaceuticals. He designed and developed cryogenic processes and equipment for Union Carbide Corporation.
As President of Goldstein Consulting Company, Dr. Goldstein provides analysis of biotechnology, food, and pharmaceutical processes and products. His work has included analyzing construction defects, memorabilia/art damage and harmful results to personnel as a consequence of industrial accidents. He provided critical input to aid in commercialization of a new biofuels process. He resolved a chemical process failure situation to aid a client. He has provided services as an Expert Witness that include research and testimony to successfully resolve cases on the behalf of clients.
As Coordinator of the Biotechnology Center of UNLV (2003-2008), Dr. Goldstein developed new business in training, laboratory service, and guiding entrepreneurial businesses with interest in establishing enterprises in the Las Vegas Valley. Specific programs that were offered (and in development) included forensic DNA profiling, assistance in training professionals for cross examination, microbiological identification and profiling, food safety, genetic basis for biotechnology improvements, weapons of mass destruction training, and prevention of nosocomial infections.
He has transferred technology and lectured on engineering and science throughout the world. He is listed in American Men of Science and Who's Who. He organized local publicity and programmed select events for the Silicon Valley Society of Competitive Intelligence Professionals. As Chair of the Northern California Pharmaceutical Discussion Group, he organized monthly events involving 100+ attendees while doubling the organization's cash position.
He is a Registered Professional Engineer and taught in the graduate school at the University of Notre Dame. Dr. Goldstein received his BS degree in chemical engineering from the Illinois Institute of Technology and his MS and Ph.D. degrees in chemical engineering from the University of Notre Dame. He holds an MBA from Michigan State University. He has 26 publications to his credit. Recently (2010), he had Sick Building Syndrome and related Illness: Prevention and Remediation of Mold Contamination published, and his book entitled Pharmaceutical Accumulation in the Environment: Prevention, Control, Health Effects, and Economic Impact is proceeding toward publication in 2014, He has co-authored books entitled Technology Transfer of Plant Biotechnology, and Plant Cell and Tissue Culture for the Production of Food Ingredients.
He solved critical problems and developed important prototypes of Miles' diagnostic devices, directed the development of their fermentation products, and guided establishment of their molecular biology program and therapeutic protein development. He led development of immobilized cell processes and provided guidance and leadership for Miles' flavor and food ingredients businesses. Dr. Goldstein led a team to solve a critical impurity problem in a Miles extraction process. He introduced pilot plant computer technology for fermentation control at Miles. His leadership in quickly correcting process/product malfunctions saved Miles many millions of dollars on different occasions. He led numerous worldwide start-ups.
He is recognized for his contributions to developing ESCAgenetics plant cell tissue culture technology and for leading efforts on vanilla flavor and the anti-cancer therapeutic Taxol. He guided critical crop harvests where an error in timing would have meant loss of an expensive product, and he rebuilt their plant genetics programs. His leadership resulted in the assembly of intellectual property in cell culture. His leadership in coaching the tissue culture date palm program resulted in a line of plants for shipment to ex-U.S. locales. He identified collaborators and personnel at critical times for the company's genetics and flavor programs.
In his consulting practice, Dr. Goldstein has applied his modeling methods to structure business relationships and optimize economics. He has guided the planning and development of manufacturing for novel new processes to produce proteins. He has directly designed, specified, and organized installation of biotechnology facilities. His past consulting activities and accomplishments include:
Industrial Background and Accomplishments
Applied to: fermentation, cell culture, construction defects, memorabilia damage analysis, dietary supplements, therapeutic proteins, small molecule therapeutic substances, novel plant growth formulations, regulatory compliance, aseptic processing for heat-sensitive materials, delivery technologies/products, safety and risk analyses. Examples include:
ESCAgenetics Corp., San Carlos, CA
Secured an $800,000 National Cancer Institute grant, developed bioreactor/process technology, and devised/implemented a strategy to obtain intellectual property protection for the anti-cancer drug, Taxol.
Secured collaborations for plant-sourced drugs of $500 million potential.
Established a competitive intelligence system. Guided development of plant genetics, immunochemical detection methods, and flavor improvement for beverages.
Guided securing intellectual property in key cases of a unique flavor system and an anti-cancer therapeutic where challenges from government and industry were successfully overcome.
Bayer Corporation(Miles, Inc.), Elkhart, IN
Led development of an FDA-approved immobilized cell bioreactor process, profitable $200million joint venture facility, start-up of domestic and ex-US bioprocessing plants, and problem solving to secure supply contracts. Led development of analytical methods critical to success of this program.
Secured qualification of $50 million/yr business at a major consumer/health care company and led development of probiotics for health care applications.
Coached a team to stabilize a cell line to produce a protein for sale to a $billion therapeutic market. Led a team that received a corporate award for developing enzymes for a world market.
Transformed a pilot plant operation into a high quality engineering research team. Shortened development time by 1/3 for $50 million products. Solved an impurity problem in a liquid extraction process for a $200 million/yr product.Return to Top